Cancer and Autoimmunity
by ME Gershwin (9780444503312)

Of the two disciplines in parallel development, tumor immunology and transplantation immunology, the latter has thrived and has led to some of the most critical discoveries in immunobiology. The former continues to thwart both scientists and clinicians alike. The goal of immunologists is to develop a simple and effective means to manipulate cancer in vivo, possibly encompassing several venues: identifying a phenotypic marker and the use of either active or passive immunization; include the use of passive reagents carrying "warheads" to selectively destroy cancer cells; or altering the basic process of cell survival. The papers in this volume include both basic and clinical science and range from sophisticated molecular biology to little more than phenomenology (for example, the increased association of cancer in some autoimmune diseases and increased presentation of autoimmune phenomena in malignant condition).

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