A Novel Taylor-Couette Bioreactor for Mammalian Cell Cultivation
by Timm Tanzeglock (9783838107059)

A Novel Taylor-Couette Bioreactor for Mammalian Cell Cultivation
 

Timm Tanzeglock


Release Date: 01 May 2009
Format: Paperback
Pages: 124
Category: Biotechnology
Publisher: Sudwestdeutscher Verlag Fur Hochschulschrifte
ISBN: 9783838107059
ISBN-10: 3838107055



In the pharmaceutical industry mammalian cell lines are the primary expression system in the production of therapeutic recombinant proteins. Despite its diverse drawbacks, the stirred tank reactor serves here as major workhorse for most applications. To overcome the limitations faced, improved bioreactors are needed to provide a more favorable in vitro environment to mimic in vivo conditions. In order to establish a suitable culture system, the cell's responsiveness to environmental stress is evaluated to identify and anticipate the impact of this process parameter during cell cultivation. Based on these studies, a novel bioreactor featuring good mass transfer characteristics at low shear values both in maximal magnitude as well as distribution is constructed. Its unique cultivation microenvironment enhances cell growth and protein production and makes it superior to conventional stirred tank reactors. Especially nowadays in the environment of a fast growing and competitive market, governmental price control and rising quality requirements, the proposed bioreactor provides a suitable tool for biopharmaceutical research, development, and production.

AUD $167.95

 This title is not held in stock & is ordered from suppliers, subject to availability.



Write a customer review of A Novel Taylor-Couette Bioreactor for Mammalian Cell Cultivation.



If you like this title please tell others:

tell others

post to your Facebook wall post on Twitter post on Digg recommend to Stumbleupon bookmark on Delicious RSS feed send to a friend


Australian BookShop
Australian Bookshop. Established 2003
Search
Shopping Cart Customer Support


HolisticPage
International Online Store
of Inspiration
we ship everywhere
Australia Post
Australia Wide
.
Worldwide