Adme: In Vitro-In Vivo Extrapolation
by Geoffrey T Tucker;Amin Rostami-Hodjegan (9781420077353)

Adme: In Vitro-In Vivo Extrapolation

Geoffrey T Tucker;Amin Rostami-Hodjegan

Release Date: 01 January 2009
Format: Hardcover
Pages: 350
Category: Pharmacology
ISBN: 9781420077353
ISBN-10: 142007735X

This comprehensive text focuses on the systems approach to simulating and predicting pharmacokinetic behavior (including metabolism-based drug-drug interactions), in patient populations using demographic, physiological, and genetic information, as well as input from in vitro studies of drug absorption and disposition. "ADME" emphasizes the use of direct experimental in vitro data obtained from human material (microsomes, cells, tissue slices, recombinant proteins) supported with prediction of relevant parameters from physicochemical properties.

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AUD $515.95

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