Cellular Responses to Arsenic: DNA Damage and Defense Mechanisms
by X Lee;Y Ed Weinfeld MLee (9781843398806)

Cellular Responses to Arsenic: DNA Damage and Defense Mechanisms

X Lee;Y Ed Weinfeld MLee

Release Date: 01 February 2005
Format: Paperback / softback
Pages: 168
Category: Biochemistry
Publisher: IWA Publishing (Intl Water Assoc)
ISBN: 9781843398806
ISBN-10: 184339880X

Although ingestion of high levels of arsenic is believed to cause certain cancers, estimates of cancer risk resulting from exposure to low levels of arsenic are the subject of considerable debate. An improved understanding of arsenic toxicity and the dose-response relationship for relatively low levels of arsenic could improve the risk assessment process. The overall objective of this study was to contribute to a better understanding of arsenic health effects. A specific aim was to investigate the cellular response of exposure to arsenic. This includes the analysis of cells treated with arsenic alone or in combination with other DNA-damaging agents in order to identify mechanisms of DNA damage, the influence of arsenic on DNA repair, and potential critical genes responsible for repair of DNA damage.

AUD $263.95

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