Retinoids in Normal Development and Teratogenesis
by Gillian Morriss-Kay (9780198547709)

Retinoids in Normal Development and Teratogenesis
 

Gillian Morriss-Kay


Format: Hardback
Pages: 320
Category: Developmental Biology
Publisher: Oxford University Press
ISBN: 9780198547709
ISBN-10: 0198547706



Retinoic acid is of major importance in the regulation of normal gene expression in both embryonic and adult cells, through binding to, and activation of, specific retinoic acid receptors in the nucleus. Other nuclear receptors may bind to different retinoids. In the embryo, tissue and stage-specific distribution patterns of the different receptors, and of the cytoplasmic retinoid binding proteins, provide an underlying basis for the richly varied and changing pattern of retinoid-related developmental gene expression. This book provides an up-to-date review of recent progress in understanding the roles of retinoids in both normal and abnormal differentiation, morphogenesis, and pattern formation. It includes molecular, cellular and embryonic approaches, which are integrated wherever possible.

AUD $170.00

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