Study of Early Spectral Changes in Cell Transformation
by Evgeny Bogomolny (9783639144369)

Study of Early Spectral Changes in Cell Transformation
 

Evgeny Bogomolny


Release Date: 01 April 2009
Format: Paperback
Pages: 124
Category: Biophysics
Publisher: VDM Verlag
ISBN: 9783639144369
ISBN-10: 3639144368



Fourier Transform Infra-Red Microspectroscopy and Light Induced Fluorescence are two potentially powerful analytical methods for identifying the spectral properties of biological activity in cells. The goal of the present research is the implementation of both spectroscopic methods in tandem in order to study early spectral changes accompanying cancerous transformation. As a model for this purpose we used two kinds of cell cultures: Murine Fibroblast cell line and Murine Embryonic Fibroblast cells. The cell cultures were infected with Murine Sarcoma Virus, which induced cancerous transformation. The spectral measurements were taken at various post infection time intervals. Our results showed FTIR-MSP and LIF spectroscopic methods as promising optical tools for diagnosis of early stages of malignancy which is essential requirement for successful cancer treatment that cannot be accomplished by conventional methods (such as CT or MRI). Moreover, these methods are complimentary and shed light on the basic cellular metabolic changes occurring during the transformation, giving a better understanding of the carcinogenesis process.

AUD $119.95

 This title is not held in stock & is ordered from suppliers, subject to availability.



Write a customer review of Study of Early Spectral Changes in Cell Transformation.



If you like this title please tell others:

tell others

post to your Facebook wall post on Twitter post on Digg recommend to Stumbleupon bookmark on Delicious RSS feed send to a friend


Australian BookShop
Australian Bookshop. Established 2003
Search
Shopping Cart Customer Support


HolisticPage
International Online Store
of Inspiration
we ship everywhere
Australia Post
Australia Wide
.
Worldwide