Transformation of Human Diploid Fibroblasts: Molecular and Genetic Mechanisms
by George E Milo;Milo E Casto Bruce CMilo (9780849349560)

Transformation of Human Diploid Fibroblasts: Molecular and Genetic Mechanisms
 

George E Milo;Milo E Casto Bruce CMilo


Release Date: 15 May 1990
Format: Hardback
Pages: 304
Category: Oncology
Publisher: Taylor and Francis
ISBN: 9780849349560
ISBN-10: 0849349567



This comprehensive publication draws together the important aspects of carcinogen-cell interaction. This interesting work describes the regulation of normal cell proliferation, cellular responses to carcinogen damage, the biologic consequences of cellular DNA modification, the structural and genomic changes resulting from carcinogen insult, and the possible involvement of such changes in the conversion of normal human fibroblasts to malignant cells. It presents current reviews with up-to-date literature references and provides critical information from leading investigators that is essential in understanding the biology of human cell transformation. This volume is especially useful to advanced students in genetic toxicology, molecular biologists, and all who are interested in the molecular and macromolecular changes in human cells leading to neoplasia.

AUD $972.00

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